Polycystic Kidney Disease (PKD)

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DR K TAMILSELVAN

Polycystic Kidney Disease (PKD)

Polycystic kidney disease (PKD) is an inherited disorder in which clusters of cysts develop primarily within your kidneys. Cysts are noncancerous round sacs containing water-like fluid. The cysts vary in size and, as they accumulate more fluid, they can grow very large.

Although kidneys usually are the most severely affected organs, polycystic kidney disease can cause cysts to develop in your liver and elsewhere in your body. The disease causes a variety of serious complications.

Shape and size of the Kidney

Structure of the normal kidney to compare with Polycystic Kidney Disease (PKD)

Types of Polycystic kidney disease (PKD) 

There are two types of polycystic kidney diseases.That includes         

         1. Autosomal dominant Polycystic Kidney disease (ADPKD)

        2.  Autosomal Recessive Polycystic Kidney Disease (ARPKD)

        Rare and usually fatal before 1 year of life.

Autosomal dominant polycystic kidney disease (ADPKD). Signs and symptoms of ADPKD often develop between the ages of 30 and 40. In the past, this type was called adult polycystic kidney disease, but children can develop the disorder.

ADPKD sturcture

Image of Autosomal dominant Polycystic kidney disease(PKD)

Only one parent needs to have the disease in order for it to pass along to the children. If one parent has ADPKD, each child has a 50 percent chance of getting the disease. This form accounts for about 90 percent of cases of polycystic kidney disease.

Autosomal recessive polycystic kidney disease (ARPKD). This type is far less common than is ADPKD. The signs and symptoms often appear shortly after birth. Sometimes, symptoms don’t appear until later in childhood or during adolescence.

ARPKD

Sturucture of Autosomal Recessive Polycystic Kidney Disease (ARPKD) Polycystic Kidney Disease (PKD)

Both parents must have abnormal genes to pass on this form of the disease. If both parents carry a gene for this disorder, each child has a 25 percent chance of getting the disease.

Clinical features of ADPKD

Pain in the renal angles, haematuria, headache

Gastronitestinal complaints

Nocturia, frequently, polyuria

Slowly developing hypertension

Both kidneys palpated and surface nodular

Uremia in late stages

Other systemic involvement in ADPKD

  1. Genetourinary

Hypernephroma, renal calculi, ovarian cyst

        B. Gastro intestinal

Hepatic cysts, pancreatic cysts, diverticuli

       C. C.V.S

Hypertension, aortic and mitral valve abnormalities, thoracic aortic aneurysm

       D. Central Nervous System

Berry aneursms (Subarachnois haemorrahage)

       E. Haematopoietic

Erythrocytosis

Diagnosis of Polycystic Kidney Disease (PKD)

Clinical features and family history of polycystic disease.

Renal ultra sonogrphy : Demonstrates bilateral renal cysts; follow up renal ltrasound in 2-3 years may show increasing renal cystic involvement.

Total abdominal ultrasonography : may be done to demonstrate hepatic, pancreatic, ovarian cysts.

CT Scan of abdomen

Treatment for PKD

Haematuria : Bed rest, analgesics, hydration

Bladder and renal parenchymal infection,hypertension, subarachnois haemorrahage

Avoiding renal trauma.

Complications of Polycystic Kidney Disease

A common complication of polycystic kidney disease is high blood pressure. Kidney failure is another common problem for people with polycystic kidney disease.

Polycystic kidney disease varies greatly in its severity, and some complications are preventable. Lifestyle changes and medical treatments may help reduce damage to your kidneys from complications, such as high blood pressure.

medlight2u.com

Acne Acne vulgaris Acute Renal Failure Adrenal cortex Angina Angina Pectoris Aortic Regurgitation (AR) Aortic Stenosis (AS) Chest pain Chronic pyelonephritis Coarctation of Aorta Cough cyanosis Cystic acne Dehydration Diabetes Mellitus Diagnosis of Aortic Stenosis Dr.KTS DR K TAMILSELVAN Heart Failure Hypertension Hypokalemia Hypothyroidism Ischemic Heart Disease LBBB metabolic acidosis Mitral Incompetence Mitral insufficiency Mitral valve prolapse Nocturia papillary necrosis Patent Ductus Arteriosus PDA Polyuria Proteinuria pulmonary hypertension Pulmonary Stenosis ST Depression Symptoms of Acne Syncope Treatment for acne valvular heart disease Ventricular Septal Defect VSD Zits

DR K TAMILSELVAN

Dr.KTS/Dr.K.Tamilselvan is the Author of www.medlight2u.com (Previously till the year 2022 April it was medvin2u.com and medvin2u.net then now it became medlight2u.com).Dr.KTS/Dr.K.Tamilselvan an International Published Researcher on Oncology the theory of his own, named as “CHONP”-Carbon, Hydrogen, Oxygen, Nitrogen and Phosphorus are the molecules present in each and every biological cells while getting an abnormal physical, chemical and biological exposure cell destruction/cell growth in irregular manner occurs, later Tissue destruction/Tissue development and its complications in further (Theory connected with proved theories such as Free Radicals, Mitosis, Myosis, etc..).He describes due to modified lifestyle that decreased or increased exposure of the Biological, Chemical and Physical sources (including prolonged duration of imbalanced water intake also) can leads to carcinoma by this way of Cell injury and its methods of spreading further leads to growth on it or abnormal development of cells or by the modifications happened there which Helps to understand the causes of carcinoma. The approach to treat carcinoma also distinguish we cannot treat all the carcinomas by the same methodology such as Chemotherapy, Radiotherapy…etc is his explanation. He quoted as his belief and one of the source for the ideology குறள் 948 அதிகாரம் – 95 – மருந்து.The Tirukkural is a classic Tamil language text “நோய்நாடி நோய்முதல் நாடி அதுதணிக்கும் வாய்நாடி வாய்ப்பச் செயல்.” which means “Diagnose the illness, trace its cause, Seek the proper remedy and apply it with skill” From the text has been dated variously from 300 BCE to 5th century CE. On the base a research is ongoing for its treatment at Tokyo by a leading research institution. He is practicing as a Homoeopathic medical practitioner at South India in Tamilnadu with the goal to establish the clinic to all over the India, Hence clinic named as Hi2U Clinic/”Happy Homoepathy clinic In India To You” at Thindal,Erode District. He Studied at Nethra Homeopathy Medical College, Coimbatore/NHMC (Now it Became Martin Homoeopathy Medical College/MHMC) Graduated BHMS (Bachelor of Homoeopathic Medicine and Surgery) by the Tamilnadu Dr.MGR Medical University then M.Sc (Psy)., and PGDPA.,(Post Graduation Diploma in Public Administration) from Annamalai University and then LL.B.,(Bachelor of LAWS) from the Karnataka State Law University/KSLU.

29 thoughts on “Polycystic Kidney Disease (PKD)”

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